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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Drug-Food InteractionsCialis (tadalafil)
Drinking alcohol with PHARM
Cialis with PHARM
Drinking caffeine

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Cialis (tadalafil) can interact with certain foods and beverages, such as grapefruit and grapefruit juice, and may cause a drop in blood pressure through the..

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Cialis 5mg 28 Tablets - How It Works

What is Cialis 5mg 28 Tablets?

Cialis 5mg 28 Tablets is used to treat erectile dysfunction (impotence) in men. It contains tadalafil and its active ingredient Tadalafil. Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor which helps in the relaxation of smooth muscle cells in the penis, allowing for increased blood flow and facilitating an erection. Tadalafil is also used to treat symptoms of benign prostatic hyperplasia (BPH).

Cialis 5mg 28 Tablets - Dosage Instructions

Do not take Cialis 5mg 28 Tablets if you:

You are allergic to any ingredient in Cialis, or any ingredients present in Cialis (such as:

  • nitrates
  • arginines
  • probenecid
  • other medicines used to treat erectile dysfunction

You are taking this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, do not take the medication.

If you are not sure whether you should start taking this medicine, ask your pharmacist or doctor.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, go back to taking your regular dose. Do not take two doses at one time.

What side effects can Cialis 5mg 28 Tablets cause?

Cialis 5mg 28 Tablets can cause side effects, although not everyone experiences them. Tell your doctor if you have any side effects, especially if they're severe or if you have a prolonged erection (lasting more than 4 hours).

Stop taking Cialis and seek medical attention immediately if you experience any of the following symptoms:

  • Fainting
  • Painful erections
  • Chest pain
  • Flushing (redness of the face, neck or chest pain)
  • Indigestion
  • Stuffy or runny nose

If you experience any of the following, stop taking Cialis and seek medical attention immediately:

  • Rash
  • Difficulty breathing or swallowing
  • Difficulty urinating
  • Swelling in ankles or feet

These can be signs of an increased risk of priapism (prolonged erection) and should be treated with a lower dose of Cialis. Do not take more Cialis than directed, and do not take it until you have discussed the risks and benefits with your healthcare provider.

What if I miss a dose?

The most common side effects of Cialis 5mg 28 Tablets are headache, flushing, indigestion, and nasal congestion. If you experience any of the following, stop taking Cialis and contact your doctor immediately:

  • Headache
  • Flushing
  • Nasal congestion

If you experience any of the above side effects, contact your doctor or pharmacist immediately.

What should I know before taking Cialis 5mg 28 Tablets?

Do not take Cialis 5mg 28 Tablets if you are allergic to any ingredients in Cialis. Before taking this medication, tell your doctor if you have ever had an allergic reaction to any medicines, foods, preservatives or dyes.

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